Saturday, February 12, 2011

Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients PDF

Rating: (95 reviews) Author: Ben Goldacre ISBN : 9780865478008 New from $15.22 Format: PDF
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We like to imagine that medicine is based on evidence and the results of fair testing and clinical trials. In reality, those tests and trials are often profoundly flawed. We like to imagine that doctors who write prescriptions for everything from antidepressants to cancer drugs to heart medication are familiar with the research literature about a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by the pharmaceutical industry. We like to imagine that regulators have some code of ethics and let only effective drugs onto the market, when in reality they approve useless drugs, with data on side effects casually withheld from doctors and patients.
     All these problems have been shielded from public scrutiny because they’re too complex to capture in a sound bite. But Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct in the medical industry affects us on a global scale.
     With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for regulation. This is the pharmaceutical industry as it has never been seen before.
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  • Hardcover: 448 pages
  • Publisher: Faber & Faber; Reprint edition (February 5, 2013)
  • Language: English
  • ISBN-10: 0865478007
  • ISBN-13: 978-0865478008
  • Product Dimensions: 1.5 x 6 x 8.5 inches
  • Shipping Weight: 1.4 pounds (View shipping rates and policies)

Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients PDF

It is a common claim among alt med cranks that skeptics are only critical of alternative medicine. This is not and has never been true - most of Bad Science is about "Big Pharma" and its shenanigans, but this latest book by Ben Goldacre goes a lot further.

In "Bad Pharma" you will read about the ways in which vested interests bamboozle us and our doctors, whether by accident or design. You will find out why the benefits of most medicines are overstated, and why the systematic review is incredibly important. You will become, in short order, very angry indeed, and then you will be told what you can do about that anger - whether you are a patient or a doctor.

Goldacre's style is engaging and informal, and he is a practising doctor. The books include anecdotes about how he himself has unknowingly prescribed drugs which are not just ineffective, but worse than doing nothing - despite having read the research evidence with a particularly critical eye. All the data and references are there if you need them but they don't derail the narrative, so the book functions both as a reference and as an eminently readable story.

This is my pick for best book of the year so far, and one of the most important books most of us will have read. This is about your health. Get informed, get angry and get active!
By Guy Chapman
Bad Pharma highlights serious issues with the way the pharmaceutical industry works today. In the book Ben highlights the problems with the industry from several angles, how the tests can be tweaked, how negative tests are not published, how you can make a neutral test appear positive by sub-dividing the goals and then emphasize the fluke positive one. He also shows how the medical journals are part of the problem and the issue with ghost written articles. He shows the problems with the regulatory side as well, for example the European Medicines Agency, their lack of transparency, and how they have effectively blocked access to critical data for researchers. All through the book Ben makes use of well documented examples, and all the issues highlighted are well documented and exemplified.

The book is written in an easy to access language, and so it reads well. He does repeat himself a bit, so one more round of editing and cleanup before release would probably have been a good idea. Some readers on amazon.co.uk have criticised this, but I don't see it as an issue.

You don't need to have a degree in medicine or a higher degree in general to understand the issues Ben highlights.

Ben Goldacre runs the Bad Science website (badscience dot net) and has previously written the book Bad Science. Where Bad Science was an attack on quackery and pseudo science, and his website to a large degree has dealt with the same topics, this book is a critical look at the pharmaceutical industry. As such it ought to silence those that have attacked Ben Goldacre for being in the pockets of the Pharmaceutical industry over time.

Ben Goldacre has done society a big favour by writing this book. I definitely recommend reading it if you want to understand more about how US and European health care works and what can be done to improve it in the future.
By Martin Orsted

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