Saturday, February 12, 2011

Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves PDF

Rating: (45 reviews) Author: George M. Church ISBN : 9780465075706 New from $17.31 Format: PDF
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“Bold and provocative… Regenesis tells of recent advances that may soon yield endless supplies of renewable energy, increased longevity and the return of long-extinct species.”—New Scientist

In Regenesis, Harvard biologist George Church and science writer Ed Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.
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  • Paperback: 304 pages
  • Publisher: Basic Books (April 8, 2014)
  • Language: English
  • ISBN-10: 0465075703
  • ISBN-13: 978-0465075706
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Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves PDF

*A full executive summary of this book is available at newbooksinbrief dot com.

DNA was only discovered about a century ago, and its structure remained a mystery until about half a century ago, but since this time our knowledge and understanding of DNA has grown immensely (indeed exponentially). What's more, this understanding has evolved to include not just an understanding of how DNA works, but also how it can be manipulated to help advance our ends. The most glaring example here is the phenomenon of genetically modified food. Though not without controversy initially (and some fringe opposition that lives on to this day), it is fair to say that genetically modified food was one of the major scientific advances of the 20th century. Over and above this, our understanding of DNA appeared to reach its most impressive manifestation with the successful sequencing of the human genome in the year 2000.

For the genetics professor and pioneering genetic engineer George Church, however, genetically modified food and the Human Genome Project are but the tip of the iceberg when it comes to the potential of genomics. Indeed, since the year 2005, the exponential growth rate in our ability to read and write DNA has increased from 1.5-fold per year (a rate that matches Moore's law), to the incredible rate of 10-fold per year (p. 243). This explosion in scientific and technological progress has resulted in dramatic advancements in the areas of biochemicals, biomaterials, biofuels and biomedicine. What's more, advancements in these technologies are but in their incipient stage, and the future of genomics promises to dwarf these initial achievements.

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