Side Effects: A Prosecutor, a Whistleblower, and a Bestselling Antidepressant on Trial PDF

Rating: (15 reviews) Author: Alison Bass ISBN : 9781565125537 New from $67.49 Format: PDF

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As the mental health reporter for the Boston Globe, Alison Bass's front-page reporting on conflicts of interest in medical research stunned readers, and her series on sexual misconduct among psychiatrists earned a Pulitzer Prize nomination. Now she turns her investigative skills to a controversial case that exposed the increased suicide rates among adolescents taking antidepressants such as Paxil, Prozac, and Zoloft.

Side Effects tells the tale of a gutsy assistant attorney general who, along with an unlikely whistle-blower at an Ivy League university, uncovered evidence of deception behind one of the most successful drug campaigns in history. Paxil was the world's bestselling antidepressant in 2002. Pediatric prescriptions soared, even though there was no proof that the drug performed any better than sugar pills in treating children and adolescents, and the real risks the drugs posed were withheld from the public. The New York State Attorney General's office brought an unprecedented lawsuit against giant manufacturer GlaxoSmithKline, the maker of Paxil, for consumer fraud. The successful suit launched a tidal wave of protest that changed the way drugs are tested, sold, and marketed in this country.

With meticulous research, Alison Bass shows us the underbelly of the pharmaceutical industry. She lays bare the unhealthy ties between the medical establishment, big pharma, and the FDA—relationships that place vulnerable children and adults at risk every day.

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• Product Details
• Table of Contents
• Reviews

• Hardcover: 260 pages
• Publisher: Algonquin Books; 1 edition (June 17, 2008)
• Language: English
• ISBN-10: 1565125533
• ISBN-13: 978-1565125537
• Product Dimensions: 6.4 x 8.9 inches
• Shipping Weight: 1.1 pounds

Side Effects: A Prosecutor, a Whistleblower, and a Bestselling Antidepressant on Trial PDF

It's horrifying to read about our dependence on drugs. I was shocked with the first story: A teenager feels uncomfortable in social situations. She sees an ad on television promising a drug to turn teens from wallflowers to social butterflies. She asks her doctor for the drug. No problem, he says. He's not a psychiatrist, but he is an MD.

Aside from concerns about effects of these drugs on children and young people, why doesn't someone ask why doctors encourage patients to seek solutions in a bottle? How is depression diagnosed (or over-diagnosed)?

Then we have a story of a psychiatrist at Brown University who appears to be billing the government for research he's not conducting. He's also adjusting research reports to discount side effects.

He's still around, still holding a prestigious position at Brown University, still receiving research grants.

Author Bass also quotes a disturbing statistic: doctors who accept money from pharmaceutical companies (for research, consulting or testifying) tend to prescribe a lot more medication than those who don't.

The fiery, likeable prosecutor battles her own vision problems as well as the pharmaceutical industry. It's frustrating to read about the legal minutiae she has to address while people are dying from these drugs. The judge's name sounds familiar: I believe she was also the judge in the Martha Stewart case.

At the end of the book, we learn that the troubled teen lost her pill-induced "suicidal ideation" after discontinuing Ambien and Paxil. She has learned to accept her personality and she's found the perfect job as a veterinary technician.

That's the good news. But as Bass reports, FDA reports still depend on doctors who accept money from drug companies, but claim they remain unbiased. Maybe they could work on a drug to cure their deep denial.

By Dr Cathy Goodwin TOP 500 REVIEWER VINE VOICE

Alison Bass brings all the players to life, both the good and the bad, in this well documented story behind the NY Attorney General's legal action against GSK. This book is in the tradition of Erin Brokavich or A Civil Action; it reads like a novel, like a thriller in fact, only it's true. No one could make this stuff up. I could not put it down. Bass deserves a lot of credit for her courage in writing this. Not only does she expose the underbelly of academic research at prestigious Ivy League schools, but also uncovers the sordid manipulation of patient advocacy groups like NAMI by pharmaceutical interests. Nothing is sacred. She goes after it all and it's a story that needs to be told in full just as it is here. I hope it will be widely read. It is a useful and exciting addition to the many books coming out about the corruption in the pharmaceutical industry, academic research, and the regulatory authorities, bringing it down to a very human level.

By Justiceseeker