Statistical Methods in Genetic Epidemiology PDF

Rating: (2 reviews) Author: Duncan C. Thomas ISBN : 9780195159394 New from $38.00 Format: PDF

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This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. Examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. Although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. It strikes a good balance between epidemiologic study designs and statistical methods of data analysis.

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• Product Details
• Table of Contents
• Reviews

• Hardcover: 464 pages
• Publisher: Oxford University Press, USA; 1 edition (January 29, 2004)
• Language: English
• ISBN-10: 019515939X
• ISBN-13: 978-0195159394
• Product Dimensions: 1 x 5.9 x 9.8 inches
• Shipping Weight: 1.8 pounds (View shipping rates and policies)

Statistical Methods in Genetic Epidemiology PDF

This is not a book about statistics,it's a book about statistical methods employed in genetic epidemiology. In fact, I would consider this the most accessible text on the subject. The entire point of this book is to address problems facing epidemiology in relation to genetics and the environment, and suggest a means to statistically measure these variables. If you're looking for a stats book, grab Sokal & Rohlf. If you're trying to address problems in genetic epi, this book is a must. Suggested equations can be found in a Multivariate Analysis Text or Sokal & Rohlf.

By Orion Graf

I bought this book for a survey course I am sitting in so as to learn genetics. This book does comprehensively review the subject and its literature, but it lacks so much as one completed example problem. Statistics is, after all, about getting the numbers right. I think this is the first time I've ever seen a book with "statistics" in its title that does not show the reader how to get the numbers right.

Don Champagne, Ph.D. (statistics & economics)

By Donald Champagne